Childers is a surname. Notable people with the surname include:

• Alisa Childers, American singer
• Ambyr Childers, American actress
• Bob Childers (1946–2006), American country/folk singer-songwriter
• Buddy Childers (1926–2007), American jazz trumpeter
• Ernest Childers (1918–2005), American Army officer
• Erskine Barton Childers (1929–1996), Irish UN civil servant
• Erskine Hamilton Childers (1905–1974), 4th President of Ireland (1973–1974)
• Hugh Childers (1827–1896), British and Australian Liberal statesman
• Jason Childers, American Major League baseball player
• Lawrence Childers, American politician
• Mary Ann Childers, American television reporter
• Marvin Childers, American politician, lawyer, and lobbyist
• Matt Childers, American major League baseball player
• Michael Childers (1784–1854), British Army officer of the Napoleonic era
• Milly Childers (1866–1922), English painter
• Molly Childers (1875–1964), American-born Irish writer
• Naomi Childers (1892–1964), American silent film actress
• Nessa Childers, Irish Member of the European Parliament
• Rita Childers (1915–2010) First Lady of Ireland
• Robert Caesar Childers (1838–1876), British orientalist
• Robert Erskine Childers (1870–1922), author and Irish nationalist
• Robert L. Childers, Tennessee judge
• Rodney Childers, American NASCAR crew chief
• Sam Childers, American charity worker
• Travis Childers, United States Representative, 1st District of Mississippi
• Tyler Childers, American singer and songwriter
• W. D. Childers, American politician, Member of the Florida Senate